Xi, who arrived here on Wednesday, is scheduled to address the opening plenary session on Friday to expound China's nuclear security policy, present China's new measures and achievements in the area and put forth a set of practical proposals on further beefing up global nuclear security, Xinhua news agency reported.
On the sidelines of the summit, Xi is expected to meet with US President Barack Obama on Thursday.
The NSS, a biennial event initiated by Obama, will this year draw together leaders and envoys from 53 countries and four international organisations, who will focus on advancing tangible improvements in nuclear security behaviour and strengthening the global nuclear security architecture.
Last week, Chinese Vice Foreign Minister Li Baodong said Beijing hopes that the summit will continuously consolidate the international consensus on nuclear security, advance national capacity-building, boost international cooperation and foster a global nuclear security culture.
The Chinese president arrived in Washington from Prague after his state visit to the Czech Republic, the first by a Chinese head of state in 67 years since the two countries established diplomatic ties. (IANS)